Calcium D-glucarate is the calcium salt of D-glucarate, a compound made in the body through the oxidation of glucose. D-glucarate is also found naturally in grapefruit, apples, oranges and cruciferous vegetables.^1,2 D-glucarate can be converted into another compound that helps the body clear steroid hormones and various toxins through a detoxification process called glucuronidation.

This active D-glucarate metabolite works by inhibiting an enzyme that reverses glucuronidation. By supporting effective detoxification, D-glucarate helps maintain optimal hormone levels and promote clearance.^1-3 It also encourages a healthy inflammatory response and offers antioxidant protection.^4-6

Calcium D-glucarate has been shown to support normal cell division in laboratory studies.^7-9 In addition, D-glucarate has been found to help maintain already-healthy levels of cholesterol and other lipids.²